Methadone Clinics in Mississippi

Methadone for opioid use disorder in Mississippi comes from opioid treatment programs. These clinics hold federal certification and DEA registration and answer to state rules set by the Mississippi Department of Mental Health. Listings on this page sit in places such as D’Iberville, Walls, Meridian and Flowood, so the drive matters as much as the program.

Each listing draws on government treatment registers, state licensing records, accreditor listings and details supplied by the providers themselves. Use the listings to compare medications offered, payment types, hours and languages. Then call intake staff to confirm what applies to you.

Rehab Centers Near You

4 Methadone Treatment Clinics in Mississippi

Jackson Comprehensive Treatment Center – Jackson
1935 Lakeland Drive, Suite 900, Jackson, Mississippi, 39216
4.5★★★★★72
Joint Commission
DetoxOutpatientTelehealth+1
Accepts InsuranceAccepts MedicaidAccepts Medicare+3
Co-occurring DisordersMATMethadone+10

Treatment at Jackson Comprehensive Treatment Center – Jackson runs from 1935 Lakeland Drive, Suite 900 in Jackson, Hinds County, Mississippi, covering addiction detox, medication-assisted treatment (MAT) and outpatient services (OP). Care is provided on an outpatient basis, so people continue…

View facility(601) 718-2468 ext. 201

Substances treated

Adderall Rehab · Alcohol Detox · Alcohol Medication Treatment · Alcohol Only Rehab · Alcohol Rehab · Beer Addiction Treatment · Binge Drinking Treatment · Carfentanil Rehab · Chronic Pain and Substance Use · Codeine Rehab · +37 more

Levels of care

Aftercare and Continuing Care · Alcohol Detox Program · Buprenorphine-Assisted Detox · Carfentanil Detox Program · Codeine Detox Program · Continuing Care · Detox by Substance · Detox Centers · Discharge Planning · Evening Treatment · +27 more

Therapies

12 Step Rehab · Addiction Counseling · Anger Management · Brief Intervention · Cognitive Behavioral Therapy (CBT) · Contingency Management · Counseling and Therapy · Couples Counseling · Evidence-Based Therapy · Family Therapy · +4 more

Mental health

Co-Occurring Mental Health Conditions · Depression and Trauma · Mental Health Conditions · Psychosocial Rehabilitation · Social Skills Training · Trauma Treatment

Groups served

Active Duty Military Detox · Active Duty Military Dual Diagnosis Rehab · Active Duty Military Medicare Rehab · Active Duty Military Outpatient Rehab · Active Duty Military Rehab · Active Duty Military Suboxone · Active Duty Military Telehealth · Active Duty Military Trauma Rehab · Active Duty Military TRICARE Rehab · Adult Rehab · +71 more

Support services

Community Outreach · Employment Support · Health and Wellness Support · Health Education · Housing and Employment Support · Housing Assistance · Peer Support · Practical Support · Recovery Support Services · Self Help Groups · +1 more

Insurance accepted

Medicaid · Medicare · Mississippi Medicaid · TRICARE · VA Community Care

Desoto County Treatment Center – Walls
8900 Delta Bluffs Cove, Walls, Mississippi, 38680
3.9★★★★☆34
CARF accredited
DetoxOutpatientAftercare
Accepts InsuranceAccepts MedicaidAccepts Medicare+4
MATMethadoneTrauma-informed+5

Treatment at Desoto County Treatment Center – Walls runs from 8900 Delta Bluffs Cove in Walls, DeSoto County, Mississippi, covering addiction detox, medication-assisted treatment (MAT) and outpatient services (OP). Care is provided on an outpatient basis, so people continue living…

View facility(662) 510-4660

Substances treated

Adderall Rehab · Carfentanil Rehab · Codeine Rehab · Concerta Rehab · Dexedrine Rehab · Fentanyl Patch (Duragesic) Rehab · Fentanyl Rehab · Heroin Rehab · Hydrocodone Rehab · Hydromorphone (Dilaudid) Rehab · +28 more

Levels of care

Aftercare and Continuing Care · Buprenorphine-Assisted Detox · Carfentanil Detox Program · Codeine Detox Program · Continuing Care · Detox by Substance · Detox Centers · Discharge Planning · Evening Treatment · Fentanyl Detox Program · +26 more

Therapies

Addiction Counseling · Brief Intervention · Cognitive Behavioral Therapy (CBT) · Counseling and Therapy · Evidence-Based Therapy · Family Therapy · Group Therapy · Individual Therapy · Motivational Interviewing

Mental health

Psychosocial Rehabilitation · Social Skills Training

Groups served

Adult Rehab · Early HIV Intervention · HIV and Hepatitis Care · Men's Medicare Rehab · Men's Outpatient Rehab · Men's Rehab · Men's TRICARE Rehab · Rehab for Domestic Violence Survivors · Trauma Informed Rehab · Women's Medicare Rehab · +4 more

Support services

Case Management · Community Outreach · Peer Support · Practical Support · Recovery Support Services · Self Help Groups · Suicide Prevention Services

Insurance accepted

Aetna · Ambetter (Centene) · Carelon Behavioral Health · Cigna Healthcare · Curative Health Plan · Humana · Magnolia Health Plan · Medicaid · Medicare · Mississippi Medicaid · +6 more

Biloxi Treatment Center – Biloxi
1989 Pass Road, Biloxi, Mississippi, 39531
3.6★★★★☆54
CARF accredited
IOPOutpatientAftercare
Accepts InsuranceAccepts MedicaidAccepts Medicare+4
MATMethadoneSeniors+6

Based at 1989 Pass Road in Biloxi, Harrison County, Mississippi, Biloxi Treatment Center – Biloxi provides intensive outpatient program (IOP), medication-assisted treatment (MAT) and outpatient services (OP). Care runs to a scheduled timetable, so people return home outside sessions. Anyone…

View facility(228) 207-1248 ext. 26405

Substances treated

Adderall Rehab · Carfentanil Rehab · Codeine Rehab · Concerta Rehab · Dexedrine Rehab · Fentanyl Patch (Duragesic) Rehab · Fentanyl Rehab · Heroin Rehab · Hydrocodone Rehab · Hydromorphone (Dilaudid) Rehab · +24 more

Levels of care

Aftercare and Continuing Care · Continuing Care · Discharge Planning · Evening Treatment · Intensive Outpatient Program (IOP) · Non-12-Step Rehab · Outpatient MAT Clinic · Outpatient Rehab · Overdose Prevention Education · Post-Treatment Follow-Up · +2 more

Therapies

Addiction Counseling · Anger Management · Cognitive Behavioral Therapy (CBT) · Counseling and Therapy · Evidence-Based Therapy · Family Therapy · Group Therapy · Individual Therapy · Motivational Interviewing · Trauma Therapy

Mental health

Psychosocial Rehabilitation · Social Skills Training

Groups served

Adult Rehab · Hepatitis Support Services · HIV and Hepatitis Care · HIV Support Services · Men's Medicare Rehab · Men's Outpatient Rehab · Men's Rehab · Pregnant Women IOP · Pregnant Women MAT · Pregnant Women Medicare Rehab · +14 more

Support services

Community Outreach · Health and Wellness Support · Health Education · Intervention Services · Peer Support · Practical Support · Recovery Support Services · Suicide Prevention Services

Insurance accepted

Aetna · Ambetter (Centene) · Carelon Behavioral Health · Cigna Healthcare · Curative Health Plan · Humana · Magnolia Health Plan · Medicaid · Medicare · Mississippi Medicaid · +6 more

HamiltonDavis Treatment Services – Meridian
2419 10th Street, Suite 210, Meridian, Mississippi, 39301
Joint Commission
DetoxPHPIOP+3
Accepts InsuranceAccepts MedicaidAccepts Medicare+4
Co-occurring DisordersMATMethadone+11
Deaf and HoH

HamiltonDavis Treatment Services – Meridian is located at 2419 10th Street, Suite 210 in Meridian, Lauderdale County, Mississippi and delivers addiction detox, intensive outpatient program (IOP), medication-assisted treatment (MAT), outpatient services (OP) and partial hospitalization program (PHP). Care runs to…

View facility(601) 932-8991 ext. 3

Substances treated

Adderall Rehab · Alcohol Detox · Alcohol MAT Friendly · Alcohol Medication Treatment · Alcohol Only Rehab · Alcohol Rehab · Ativan (Lorazepam) Rehab · Beer Addiction Treatment · Benzodiazepine Rehab · Binge Drinking Treatment · +54 more

Levels of care

Aftercare and Continuing Care · Alcohol Detox Program · Ativan (Lorazepam) Detox Program · Benzodiazepine Detox Program · Buprenorphine-Assisted Detox · Carfentanil Detox Program · Clonidine and Lofexidine Detox · Cocaine Detox Program · Codeine Detox Program · Continuing Care · +42 more

Therapies

12 Step Rehab · Activity Therapy · Addiction Counseling · Anger Management · Brief Intervention · Cognitive Behavioral Therapy (CBT) · Community Reinforcement Approach · Contingency Management · Counseling and Therapy · Couples Counseling · +10 more

Mental health

Co-Occurring Mental Health Conditions · Crisis Intervention · Depression and Anxiety · Depression and Trauma · Mental Health Conditions · Mental Health Crisis Services · Mental Health Treatment · Psychosocial Rehabilitation · Serious Mental Illness Treatment · Social Skills Training · +1 more

Groups served

Active Duty Military Detox · Active Duty Military Dual Diagnosis Rehab · Active Duty Military Medicare Rehab · Active Duty Military Outpatient Rehab · Active Duty Military Rehab · Active Duty Military Suboxone · Active Duty Military Telehealth · Active Duty Military Trauma Rehab · Active Duty Military TRICARE Rehab · Adult Rehab · +95 more

Support services

Case Management · Community Outreach · Education and Job Training · Employment Support · Health and Wellness Support · Health Education · Housing and Employment Support · Housing Assistance · Intervention Services · Peer Support · +6 more

Languages

Deaf and Hard of Hearing Detox · Deaf and Hard of Hearing Dual Diagnosis Rehab · Deaf and Hard of Hearing MAT · Deaf and Hard of Hearing Rehab

Insurance accepted

Medicaid · Medicare · Mississippi Medicaid · TRICARE

Rehabs by setting in Mississippi

Other parts of Mississippi, and what each is near.

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Common questions about Methadone Clinics

Answered from what is listed here.

Which Mississippi cities have methadone clinics?

D'Iberville, Walls, Meridian and Flowood are the Mississippi cities where methadone clinic listings cluster, and those locations sit within reach of Gulfport, the Memphis area and Meridian. Because daily dosing often means frequent visits early on, travel time to whichever clinic is closest deserves careful thought.

Rehab Centers in Wallshttps://rehabseekers.com/locations/us/mississippi/walls/
Can I use Mississippi Medicaid for methadone treatment?

Nearly all of the methadone clinics in Mississippi accept Mississippi Medicaid, according to their own records. Coverage often runs through a MississippiCAN plan, depending on how the member enrolled.

Magnolia Health, Molina Healthcare and TrueCare are MississippiCAN plans whose coverage includes behavioral health services. Before a first visit, members can call their plan and the clinic's intake staff to confirm methadone dosing and counseling are covered together.

Rehab Centers in Mississippi That Accept Mississippi Medicaidhttps://rehabseekers.com/locations/us/mississippi/mississippi-medicaid/
Which methadone clinics in Mississippi are close to a river?

Nearly all of the methadone clinics in Mississippi sit within 25 miles of a river, measured from each listed clinic. The most-named rivers are the Biloxi River, the Wolf River and the Chunky River.

Across the state, the nearest river is a median of about 15.2 miles from listed clinics. Because methadone care usually means regular clinic visits, closeness to home or work tends to matter more to patients than any river.

Rehab Centers Near Rivershttps://rehabseekers.com/attractions/rivers/

How do methadone clinics work in Mississippi?

Methadone clinics in Mississippi are federally certified opioid treatment programs that dispense methadone on site, under registration with the Drug Enforcement Administration (DEA), usually alongside counseling. Methadone for opioid use disorder cannot be picked up at a regular pharmacy, so patients take doses at the clinic, under observation at first. Many programs also offer buprenorphine or naltrexone.

Mississippi clinics follow Chapter 53 of the state rules on opioid treatment services, and the Department of Mental Health oversees them through its Bureau of Alcohol and Drug Services. Admission usually means an intake interview, a physical exam and a drug screen, and some clinics give a first dose the same day or the next when the schedule allows.

Take-home doses come gradually under federal rules revised in 2024, with up to 7 allowed in the first 14 days and more as treatment continues, always subject to a clinician’s judgment of stability. Payment routes include MississippiCAN plans under Medicaid, Medicare Part B at enrolled clinics, private insurance and weekly self-pay fees.

All the methadone listings in Mississippi sit within 25 miles of a river, a median of 15.2 miles away, with the Biloxi, Wolf and Chunky among the nearest. The median drive to the closest airport is 5.3 miles, with Gulfport Biloxi International, the Memphis airport and Key Field in Meridian nearby. Most listings are in towns, at a median elevation of 220 feet.

Distance, guest dosing and transfers

Methadone access in Mississippi is uneven, so travel planning is part of treatment. Listings sit on the Gulf Coast, in Flowood near Jackson, in Meridian and in DeSoto County near Memphis. Much of the Delta and the rural east relies on regional community mental health centers. Your home clinic can arrange guest dosing with another OTP in advance if you travel, and a transfer needs records sent between programs. Office-based buprenorphine is a separate option; see Suboxone clinics in Mississippi.

How do you start methadone treatment, and can you begin the same day?

Starting methadone in Mississippi involves an intake assessment, a medical exam and a drug test. Some clinics give the first dose the same day or the next day when their schedule allows. No program can promise same-day admission, so calling early helps. Federal rules revised in 2024 dropped the old requirement of a full year of opioid dependence before admission. Bring photo ID, insurance or Medicaid cards, a list of current medications and records from past treatment.

Dosing windows at Mississippi OTPs usually open early in the morning. Clinical staff begin with a low dose and raise it gradually. Pregnant people have priority in Mississippi: DMH says preference is given to pregnant women at all DMH certified programs, with referral for interim services if admission isn’t available within 48 hours. Programs noting this appear under rehab for pregnant women in Mississippi.

When can you get take-home doses of methadone in Mississippi?

Take-home methadone in Mississippi follows the federal schedule in 42 CFR Part 8, revised in 2024. The schedule allows up to 7 take-home doses in the first 14 days of treatment, up to 14 from day 15, and up to 28 from day 31. All take-homes depend on a clinician’s judgment of stability. Mississippi’s Chapter 53 rules and each program’s own policy can add conditions, so ask the admissions team how take-homes are decided there.

Safety with methadone at home

Methadone dose changes should happen only under clinic supervision. The medication builds up in the body over the first days and can slow breathing. Alcohol, benzodiazepines, sleep aids and other sedatives raise that risk. Take-home doses belong in a locked box, out of reach of children. Naloxone is easy to get in Mississippi: a statewide standing order from the State Health Officer, dated March 2, 2026, lets pharmacists dispense it to any person regardless of age. The state’s Good Samaritan law protects people who seek help during an overdose from arrest or prosecution for a drug violation.

Does Mississippi Medicaid, Medicare or private insurance pay for methadone?

Medicare Part B has covered opioid treatment program services since 2020, and Mississippi Medicaid’s managed care plans cover behavioral health services. Even so, confirm methadone coverage with both the plan and the clinic before the first visit.

PaymentWhat to know
Mississippi MedicaidRun through MississippiCAN plans: Magnolia Health, Molina Healthcare and TrueCare. Mississippi has not expanded Medicaid to most adults.
MedicarePart B covers methadone, counseling and testing at OTPs enrolled in Medicare.
Private insurancePlans vary. Ask whether the OTP is in network and needs prior authorization.
Self-payMany clinics charge a weekly fee. Ask for it in writing.
Grant fundingDMH runs federal State Opioid Response funds meant to expand access to medication treatment. Ask about funded slots.

General Medicaid information sits on the RehabSeekers.com Medicaid page. Mississippi programs that bill Medicare appear under Medicare rehab in Mississippi. Without coverage, compare state-funded rehab in Mississippi and low-cost rehab in Mississippi.

Who licenses and oversees methadone clinics in Mississippi?

The Mississippi Department of Mental Health oversees methadone clinics. Its Bureau of Alcohol and Drug Services is the State Authority for Opioid Treatment Programs under Miss. Admin. Code 24-2-53.1, which names it the Bureau of Alcohol and Drug Addiction Services. The DMH Division of Certification certifies providers under the DMH Operational Standards. Federal certification and DEA registration are required as well. Where a listing shows accreditation, it comes from a named accrediting body. The DMH Helpline, 1-877-210-8513, is staffed around the clock.

Reading the methadone listings

Methadone listings for Mississippi show OTP certification as listed, medications offered, payment types and insurers, hours, languages, populations served and location. Related options include opioid rehab in Mississippi, outpatient rehab in Mississippi and detox in Mississippi. Every program type in the state is on the Mississippi locations page.