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Lofexidine (Lucemyra)

Lofexidine (Lucemyra) Treatment

Approved specifically to ease opioid withdrawal symptoms for up to fourteen days, lofexidine, sold as Lucemyra, is not an opioid. It lowers the adrenaline surge behind sweating, cramping and agitation, without treating the underlying opioid use disorder itself, which is a separate piece of the plan.

It is usually a bridge into something longer, since withdrawal support alone does not carry someone far. Listings show which facilities stock it and what they offer afterwards, including buprenorphine, naltrexone or residential care. Compare the step that follows before choosing a detox program.

Rehab Centers Near You

Top 12 Drug and Alcohol Rehab Centers Offering Lofexidine

Recovery Unplugged Nashville – Brentwood

255 Wilson Pike Circle, Brentwood, Tennessee, 37027

4.9★★★★★~~386~~

Joint Commission

DetoxHospital detoxInpatient+6

Accepts InsuranceAccepts MedicaidSelf-Pay

Co-occurring DisordersMATTrauma-informed+9

Spanish spoken

The facility sits on Wilson Pike Circle, in the Maryland Farms area of Brentwood — an affluent Williamson County suburb immediately south of Nashville. The facility offers addiction detox, alcohol withdrawal management, drug withdrawal management and dual diagnosis treatment. Both residential and outpatient care are recorded at this location. Recorded credentials include The Joint Commission, DEA and State substance use agency licence.Treatment addresses substance use alongside co-occurring mental health conditions, including anxiety disorders, co-occurring disorders…

3.7 miWhitfield Park8.9 miNashville International AirportServes13 towns

Substances treated

Adderall Rehab · Alcohol Detox · Alcohol Medication Treatment · Alcohol Only Rehab · Alcohol Rehab · Ativan (Lorazepam) Rehab · Beer Addiction Treatment · Benzodiazepine Rehab · Binge Drinking Treatment · Carfentanil Rehab · +50 more

Levels of care

14-Day Rehab · 21-Day Rehab · 30-Day Rehab · Addiction Retreat · Aftercare and Continuing Care · Alcohol Detox Program · Anxiety Retreat · Ativan (Lorazepam) Detox Program · Benzodiazepine Detox Program · Buprenorphine-Assisted Detox · +62 more

Therapies

12 Step Rehab · Activity Therapy · Addiction Counseling · Brief Intervention · Cognitive Behavioral Therapy (CBT) · Counseling and Therapy · Couples Counseling · Dialectical Behavior Therapy (DBT) · Evidence-Based Therapy · Family Therapy · +5 more

Mental health

Co-Occurring Mental Health Conditions · Depression and Anxiety · Depression and PTSD · Depression and Trauma · Family Education Programs · Mental Health Conditions · Mental Health Treatment · Psychiatric Medication Management · Psychosocial Rehabilitation · Psychosocial Rehab Services · +4 more

Groups served

Active Duty Military Detox · Active Duty Military Dual Diagnosis Rehab · Active Duty Military Outpatient Rehab · Active Duty Military PTSD Rehab · Active Duty Military Rehab · Active Duty Military Suboxone · Active Duty Military Telehealth · Active Duty Military Trauma Rehab · Adult Rehab · Couples Rehab · +74 more

Support services

Case Management · Community Outreach · Education and Job Training · Employment Support · Health and Wellness Support · Health Education · Hepatitis C Treatment · HIV Treatment · Housing and Employment Support · Housing Assistance · +8 more

Languages

Spanish Speaking Rehab

Insurance accepted

Aetna · Ambetter (Centene) · BCBS (Blue Cross Blue Shield) · Cigna Healthcare · ComPsych · Humana · Magellan Health · Optum · Sendero Health Plans · UnitedHealthcare (UHC)

Recovery Team – Newton Upper Falls

233 Needham Street, Newton Upper Falls, Massachusetts, 2464

5.0★★★★★~~118~~

Joint Commission

DetoxPHPIOP+3

Accepts InsuranceSelf-Pay

Co-occurring DisordersMATTrauma-informed+8

Recovery Team operates from 233 Needham Street in Newton Upper Falls, close enough to Newton and Needham to serve both. That radius takes in Wellesley, Brookline, Watertown and Dedham, all within 5 miles. Newton Upper Falls sits in Middlesex County, and the county's own provision is limited enough that this site draws from a wide area. The facility runs partial hospitalization, intensive outpatient and outpatient care. Medication-assisted treatment is part of the offer, the approach…

2.1 miHarvey Beach11 miBoston Logan International AirportServes61 towns

Substances treated

Adderall Rehab · Alcohol Medication Treatment · Alcohol Only Rehab · Alcohol Rehab · Beer Addiction Treatment · Binge Drinking Treatment · Carfentanil Rehab · Chronic Pain and Substance Use · Codeine Rehab · Concerta Rehab · +36 more

Levels of care

Aftercare and Continuing Care · Clonidine and Lofexidine Detox · Continuing Care · Detox by Substance · Detox Centers · Discharge Planning · Evening Treatment · Intensive Outpatient Program (IOP) · Online Rehab and Telehealth · Outpatient MAT Clinic · +6 more

Therapies

12 Step Rehab · Activity Therapy · Acupuncture · Addiction Counseling · Anger Management · Brief Intervention · Cognitive Behavioral Therapy (CBT) · Contingency Management · Counseling and Therapy · Couples Counseling · +12 more

Mental health

Co-Occurring Mental Health Conditions · Depression and Anxiety · Depression and PTSD · Depression and Trauma · Family Education Programs · Illness Management and Recovery · Mental Health Conditions · Mental Health Treatment · Psychiatric Medication Management · Psychosocial Rehabilitation · +5 more

Groups served

Active Duty Military Dual Diagnosis Rehab · Active Duty Military Outpatient Rehab · Active Duty Military PTSD Rehab · Active Duty Military Rehab · Active Duty Military Suboxone · Active Duty Military Telehealth · Active Duty Military Trauma Rehab · Adult Rehab · Couples Rehab · Court Ordered Dual Diagnosis Rehab · +49 more

Support services

Case Management · Chronic Illness Management · Community Outreach · Education and Job Training · Employment Support · Health and Wellness Support · Health Education · Hepatitis C Treatment · HIV Treatment · Housing and Employment Support · +11 more

Insurance accepted

TRICARE

Rancho Recovery – Rancho Cucamonga

13684 Jeremy Court, Rancho Cucamonga, California, 91739

5.0★★★★★64

Joint Commission

DetoxHospital detoxInpatient+6

Accepts InsuranceAccepts MedicaidAccepts TRICARE+2

Co-occurring DisordersMATTrauma-informed+8

Spanish spokenDeaf and HoH

Rancho Recovery – Rancho Cucamonga is based on 13684 Jeremy Court in Rancho Cucamonga, San Bernardino County. The facility offers addiction detox, medically supervised detox, alcohol withdrawal management, drug withdrawal management, polysubstance detox and opioid withdrawal management. Care is provided on both a residential and outpatient basis. This location is registered for both substance use and mental health treatment. Details on this page are drawn from the federal treatment locator maintained by the Substance Abuse…

6.7 miBonita Falls7.6 miOntario International AirportServes4 towns

Substances treated

Adderall Rehab · Alcohol Detox · Alcohol MAT Friendly · Alcohol Medication Treatment · Alcohol Only Rehab · Alcohol Rehab · Ativan (Lorazepam) Rehab · Beer Addiction Treatment · Benzodiazepine Rehab · Binge Drinking Treatment · +54 more

Levels of care

14-Day Rehab · 21-Day Rehab · 30-Day Rehab · 45-Day Rehab · 60-Day Rehab · 90-Day Rehab · Addiction Retreat · Aftercare and Continuing Care · Alcohol Detox Program · Anxiety Retreat · +67 more

Therapies

12 Step Rehab · Activity Therapy · Addiction Counseling · Anger Management · Brief Intervention · Cognitive Behavioral Therapy (CBT) · Community Reinforcement Approach · Contingency Management · Counseling and Therapy · Couples Counseling · +10 more

Mental health

Assertive Community Treatment (ACT) · Co-Occurring Mental Health Conditions · Depression and Anxiety · Depression and PTSD · Depression and Trauma · Family Education Programs · Mental Health Conditions · Mental Health Treatment · Psychiatric Medication Management · Psychosocial Rehabilitation · +4 more

Groups served

Adult Rehab · Couples Rehab · Court Ordered Detox · Court Ordered Dual Diagnosis Rehab · Court Ordered MAT · Court Ordered Outpatient Rehab · Court Ordered Rehab · Court Referral Accepted · Hepatitis Support Services · HIV and Hepatitis Care · +46 more

Support services

Case Management · Community Outreach · Education and Job Training · Employment Support · Health and Wellness Support · Health Education · Housing and Employment Support · Housing Assistance · Intensive Case Management · Intervention Services · +8 more

Languages

Deaf and Hard of Hearing Detox · Deaf and Hard of Hearing Dual Diagnosis Rehab · Deaf and Hard of Hearing MAT · Deaf and Hard of Hearing Rehab · Deaf and Hard of Hearing Residential Rehab · Spanish Speaking Rehab

Insurance accepted

Medicaid · TRICARE

South Shore Recovery Center – Plymouth

182 Standish Avenue, Plymouth, Massachusetts, 2360

5.0★★★★★76

Joint Commission

DetoxPHPIOP+3

Accepts InsuranceAccepts MedicaidAccepts TRICARE+3

MATSeniorsYoung adults+5

Deaf and HoH

South Shore Recovery Center is at 182 Standish Avenue in Plymouth. North Plymouth is 0.5 miles away and Kingston 2.6. Anyone within about 7 miles can reach it without a major journey, which takes in South Duxbury, Duxbury, Green Harbor and The Pinehills. Plymouth County is the relevant authority here, which matters for anyone using state-funded care. South Shore Recovery Center offers partial hospitalization, intensive outpatient and outpatient care. Medication for opioid dependence is available…

0.8 miNelson Beach25 miNew Bedford Regional AirportServes18 towns

Substances treated

Adderall Rehab · Alcohol MAT Friendly · Alcohol Medication Treatment · Alcohol Only Rehab · Alcohol Rehab · Beer Addiction Treatment · Binge Drinking Treatment · Carfentanil Rehab · Codeine Rehab · Concerta Rehab · +35 more

Levels of care

Therapies

12 Step Rehab · Activity Therapy · Addiction Counseling · Anger Management · Brief Intervention · Cognitive Behavioral Therapy (CBT) · Contingency Management · Counseling and Therapy · Couples Counseling · Dialectical Behavior Therapy (DBT) · +9 more

Mental health

Assertive Community Treatment (ACT) · Co-Occurring Mental Health Conditions · Depression and Anxiety · Family Education Programs · Mental Health Conditions · Mental Health Treatment · Psychiatric Medication Management · Psychosocial Rehabilitation · Psychosocial Rehab Services · Social Skills Training

Groups served

Adult Rehab · Couples Rehab · Court Ordered Rehab · Hepatitis Support Services · HIV and Hepatitis Care · HIV Support Services · Legal Advocacy Support · Men's Dual Diagnosis Rehab · Men's Outpatient Rehab · Men's Rehab · +15 more

Support services

Languages

Deaf and Hard of Hearing Dual Diagnosis Rehab · Deaf and Hard of Hearing MAT · Deaf and Hard of Hearing Rehab

Insurance accepted

Aetna · Anthem / Elevance Health · BCBS (Blue Cross Blue Shield) · Cigna Healthcare · Harvard Pilgrim Health Care · Humana · Medicaid · Optum · TRICARE · Tufts Health Plan

Bergen Enterprises Center LLC – Fair Lawn

22-08 Route 208, Fair Lawn, NJ, 7410

4.9★★★★★~~316~~

Joint Commission

DetoxPHPIOP+3

Accepts InsuranceAccepts TRICARESelf-Pay

Co-occurring DisordersMATTrauma-informed+6

Bergen Enterprises Center LLC is based at 22-08 Route 208 in Fair Lawn, New Jersey. It is recorded as offering intensive outpatient and outpatient care. Substance use is treated alongside mental health rather than separately. Care is provided on an outpatient basis, so people continue living at home. Remote appointments appear on the record, useful where travel is difficult. Group and family work are both recorded. Licensing sits with the New Jersey Division of Mental…

3.3 miPassaic Falls18 miNewark Liberty International AirportServes94 towns

Substances treated

Levels of care

Therapies

12 Step Rehab · Activity Therapy · Addiction Counseling · Anger Management · Cognitive Behavioral Therapy (CBT) · Counseling and Therapy · Couples Counseling · Dialectical Behavior Therapy (DBT) · Evidence-Based Therapy · Family Therapy · +7 more

Mental health

Co-Occurring Mental Health Conditions · Depression and Anxiety · Depression and Trauma · Family Education Programs · Illness Management and Recovery · Mental Health Conditions · Mental Health Treatment · Psychiatric Medication Management · Psychosocial Rehabilitation · Psychosocial Rehab Services · +2 more

Groups served

Adult Rehab · Couples Rehab · Hepatitis Support Services · HIV and Hepatitis Care · HIV Support Services · Men's Dual Diagnosis Rehab · Men's Outpatient Rehab · Men's Rehab · Men's Telehealth · Men's Trauma Rehab · +15 more

Support services

Case Management · Chronic Illness Management · Community Outreach · Employment Support · Health and Wellness Support · Health Education · Hepatitis C Treatment · HIV Treatment · Housing and Employment Support · Housing Assistance · +10 more

Insurance accepted

Aetna · BCBS (Blue Cross Blue Shield) · Carelon Behavioral Health · Cigna Healthcare · Horizon Blue Cross · MultiPlan / PHCS · NYSHIP · TRICARE · UMR

Ocean State Recovery Center – Johnston

1524 Atwood Avenue, Johnston, RI 02919

4.9★★★★★~~365~~

Joint Commission

DetoxPHPIOP+3

Accepts InsuranceAccepts MedicaidAccepts Medicare+5

Co-occurring DisordersMATTrauma-informed+9

Spanish spoken

Ocean State Recovery Center operates from 1524 Atwood Avenue in Johnston. The site sits in Providence County, which shapes which public funding routes apply. Nearby communities include Cranston and Greenville. Rhode Island draws people across long distances for treatment, so travel time is worth weighing against waiting time. Partial hospitalization, intensive outpatient and outpatient care are delivered here, alongside medication-assisted treatment, telehealth appointments and care for co-occurring mental health conditions. Which level fits depends on…

3.6 miSlacks Pond Beach8.1 miRhode Island T. F. Green International AirportServes35 towns

Substances treated

Levels of care

Therapies

Mental health

Groups served

Active Duty Military Dual Diagnosis Rehab · Active Duty Military Medicare Rehab · Active Duty Military Outpatient Rehab · Active Duty Military PTSD Rehab · Active Duty Military Rehab · Active Duty Military Suboxone · Active Duty Military Telehealth · Active Duty Military Trauma Rehab · Active Duty Military TRICARE Rehab · Adult Rehab · +72 more

Support services

Case Management · Chronic Illness Management · Community Outreach · Education and Job Training · Employment Support · Health and Wellness Support · Health Education · Housing and Employment Support · Housing Assistance · Intensive Case Management · +12 more

Languages

Spanish Speaking Rehab

Insurance accepted

Medicaid · Medicare · TRICARE

Avenues Recovery Center at Lake Ariel – Lake Ariel

50 Industrial Park Road, Lake Ariel, PA, 18436

4.8★★★★★~~411~~

Joint Commission

DetoxResidentialPHP+4

Accepts InsuranceAccepts TRICARESliding Scale+1

Co-occurring DisordersMATTrauma-informed+7

Records place Avenues Recovery Center at Lake Ariel at 50 Industrial Park Road, Lake Ariel, Pennsylvania. Provision here is recorded as detox, residential treatment and intensive outpatient. Medication for opioid use disorder is offered here alongside talking treatment. Care is delivered on an inpatient basis, with people living on site for the length of the stay. Telehealth appointments are recorded as available, which widens what is reachable for anyone without transport. Veterans and military families…

7.8 miWest Fork Lehigh River18 miWilkes-Barre/Scranton International AirportServes12 towns

Substances treated

Levels of care

Therapies

12 Step Rehab · Addiction Counseling · Anger Management · Brief Intervention · Cognitive Behavioral Therapy (CBT) · Counseling and Therapy · Couples Counseling · Evidence-Based Therapy · Family Therapy · Group Therapy · +4 more

Mental health

Co-Occurring Mental Health Conditions · Depression and Anxiety · Depression and Trauma · Mental Health Conditions · Mental Health Treatment · Psychiatric Medication Management · Trauma Treatment

Groups served

Adult Rehab · Couples Rehab · Hepatitis Support Services · HIV and Hepatitis Care · HIV Support Services · Men's Dual Diagnosis Rehab · Men's Outpatient Rehab · Men's Rehab · Men's Residential Rehab · Men's Telehealth · +21 more

Support services

Case Management · Employment Support · Health and Wellness Support · Health Education · Hepatitis C Treatment · HIV Treatment · Housing and Employment Support · Housing Assistance · Practical Support · PrEP Services · +5 more

Insurance accepted

Aetna · BCBS (Blue Cross Blue Shield) · Capital District Physicians' Health Plan (CDPHP) · Carelon Behavioral Health · Emblem Health · First Health · Geisinger Health Plan · Highmark Health · Humana · PA Health & Wellness · +3 more

Coastal Detox Inc – Stuart

1131 SE Indian Street, Stuart, FL, 34997

4.8★★★★★~~290~~

Joint Commission

DetoxHospital detoxInpatient+5

Accepts InsuranceAccepts MedicaidAccepts Medicare+4

Co-occurring DisordersMATMethadone+10

Spanish spoken

The address on record is 1131 SE Indian Street in Stuart, Florida. It is recorded as offering residential treatment, partial hospitalization and intensive outpatient. This is recorded as treating co-occurring conditions rather than one in isolation. Care runs on site, with accommodation included for the duration. Family involvement is listed as part of the provision. Federal registration is held through SAMHSA, and licensing sits with the Florida Department of Children and Families.

3.0 miSouth Fork Saint Lucie River34 miPresident Donald J. Trump International AirportServes7 towns

Substances treated

Levels of care

Therapies

12 Step Rehab · Activity Therapy · Addiction Counseling · Anger Management · Brief Intervention · Cognitive Behavioral Therapy (CBT) · Counseling and Therapy · Couples Counseling · Dialectical Behavior Therapy (DBT) · Evidence-Based Therapy · +8 more

Mental health

Co-Occurring Mental Health Conditions · Depression and Anxiety · Depression and Trauma · Family Education Programs · Mental Health Conditions · Mental Health Crisis Services · Mental Health Treatment · Psychiatric Medication Management · Psychosocial Rehabilitation · Social Skills Training · +1 more

Groups served

Active Duty Military Detox · Active Duty Military Dual Diagnosis Rehab · Active Duty Military Medicare Rehab · Active Duty Military Outpatient Rehab · Active Duty Military Rehab · Active Duty Military Suboxone · Active Duty Military Trauma Rehab · Active Duty Military TRICARE Rehab · Adult Rehab · Couples Rehab · +78 more

Support services

Case Management · Community Outreach · Health and Wellness Support · Health Education · HIV Treatment · Housing and Employment Support · Housing Assistance · Nutrition and Fitness Counseling · Peer Support · Practical Support · +5 more

Languages

Spanish Speaking Rehab

Insurance accepted

Aetna · Ambetter (Centene) · AmeriHealth · Avmed · CarePlus Health Plans · Cigna Healthcare · ComPsych · Emblem Health · First Health · Golden Rule Insurance Company · +10 more

Comprehensive Wellness Centers – Lake Worth

660 South Dixie Highway, Lake Worth, FL, 33462

4.8★★★★★~~201~~

Joint Commission

DetoxInpatientResidential+6

Accepts InsuranceAccepts MedicaidAccepts Medicare+3

Co-occurring DisordersMATTrauma-informed+8

Spanish spoken

The provider's premises are at 660 South Dixie Highway, Lake Worth, Florida. Provision here is recorded as residential treatment, partial hospitalization, intensive outpatient and sober living. Provision spans substance use and mental health together. This is residential provision, so someone lives at the facility throughout. Remote appointments appear on the record, useful where travel is difficult. Group and family work are both recorded. Both federal registration through SAMHSA and Florida Department of Children and Families…

1.3 miSouth Palm Beach7.7 miPresident Donald J. Trump International AirportServes10 towns

Substances treated

Levels of care

14-Day Rehab · 21-Day Rehab · 30-Day Rehab · 45-Day Rehab · 60-Day Rehab · 90-Day Rehab · Addiction Retreat · Aftercare and Continuing Care · Anxiety Retreat · Clonidine and Lofexidine Detox · +32 more

Therapies

Mental health

Groups served

Support services

Case Management · Community Outreach · Education and Job Training · Employment Support · Health and Wellness Support · Health Education · Housing and Employment Support · Housing Assistance · Intervention Services · Nutrition and Fitness Counseling · +9 more

Languages

Spanish Speaking Rehab

Insurance accepted

Aetna · Ambetter (Centene) · AmeriHealth · Avmed · BCBS (Blue Cross Blue Shield) · Cigna Healthcare · Devoted Health · Magellan Health · Medicare · Optum · +4 more

Recovery Team – Mountainside

1450 US-22, Mountainside, NJ, 7092

5.0★★★★★80

Joint Commission

DetoxIOPOutpatient+2

Accepts InsuranceSelf-Pay

MATYoung adultsWomen+2

Spanish spoken

The provider's premises are at 1450 US-22, Mountainside, New Jersey. Listed provision covers intensive outpatient and outpatient care. Medication for opioid use disorder is offered here alongside talking treatment. Treatment is delivered without an overnight stay, around existing commitments. Telehealth appointments are recorded as available, which widens what is reachable for anyone without transport. Dedicated support is recorded for veterans and military families. SAMHSA holds the federal registration and the New Jersey Division of Mental…

4.1 miEast Branch Rahway River10 miNewark Liberty International AirportServes83 towns

Substances treated

Levels of care

Aftercare and Continuing Care · Clonidine and Lofexidine Detox · Detox by Substance · Detox Centers · Discharge Planning · Evening Treatment · Intensive Outpatient Program (IOP) · Online Rehab and Telehealth · Outpatient MAT Clinic · Outpatient Rehab · +3 more

Therapies

12 Step Rehab · Addiction Counseling · Brief Intervention · Cognitive Behavioral Therapy (CBT) · Counseling and Therapy · Evidence-Based Therapy · Family Therapy · Group Therapy · Motivational Interviewing · Trauma Therapy

Mental health

Mental Health Treatment · Psychiatric Medication Management

Groups served

Adult Rehab · HIV and Hepatitis Care · Men's Outpatient Rehab · Men's Rehab · Men's Telehealth · Women's Outpatient Rehab · Women's Rehab · Women's Telehealth · Young Adult Rehab

Support services

Case Management · Health and Wellness Support · Hepatitis C Treatment · HIV Treatment · Housing and Employment Support · Housing Assistance · Recovery Coaching · Recovery Support Services · Suicide Prevention Services

Languages

Spanish Speaking Rehab

Insurance accepted

TRICARE

Asheville Recovery Center – Asheville

9 Old Burnsville Hill Road, Asheville, North Carolina, 28804

4.9★★★★★~~562~~

Joint Commission

DetoxPHPIOP+2

Accepts InsuranceAccepts TRICAREAccepts State Insurance+2

MATYoung adultsWomen+2

Based at 9 Old Burnsville Hill Road in Asheville, Buncombe County, North Carolina, Asheville Recovery Center – Asheville provides intensive outpatient program (IOP), medication-assisted treatment (MAT), outpatient services (OP) and partial hospitalization program (PHP). Care runs to a scheduled timetable, so people return home outside sessions. People weighing options in Asheville can compare this against nearby providers before making contact. Details here draw on the Substance Abuse and Mental Health Services Administration treatment locator, the…

3.4 miElk Mountains16 miAsheville Regional AirportServes10 towns

Substances treated

Adderall Rehab · Alcohol Medication Treatment · Alcohol Only Rehab · Alcohol Rehab · Beer Addiction Treatment · Binge Drinking Treatment · Carfentanil Rehab · Codeine Rehab · Concerta Rehab · Dexedrine Rehab · +32 more

Levels of care

Aftercare and Continuing Care · Clonidine and Lofexidine Detox · Continuing Care · Detox by Substance · Detox Centers · Discharge Planning · Evening Treatment · Intensive Outpatient Program (IOP) · Outpatient MAT Clinic · Outpatient Rehab · +5 more

Therapies

12 Step Rehab · Acupuncture · Addiction Counseling · Brief Intervention · Cognitive Behavioral Therapy (CBT) · Counseling and Therapy · Evidence-Based Therapy · Family Therapy · Group Therapy · Individual Therapy · +4 more

Mental health

Mental Health Treatment · Psychiatric Medication Management · Psychosocial Rehabilitation · Social Skills Training

Groups served

Adult Rehab · Hepatitis Support Services · HIV and Hepatitis Care · HIV Support Services · Men's Outpatient Rehab · Men's Rehab · Men's TRICARE Rehab · Women's Outpatient Rehab · Women's Rehab · Women's TRICARE Rehab · +1 more

Support services

Case Management · Health and Wellness Support · Health Education · Housing and Employment Support · Housing Assistance · Intervention Services · Peer Support · Practical Support · Recovery Support Services · Self Help Groups · +3 more

Insurance accepted

Aetna · AmeriHealth · BCBS (Blue Cross Blue Shield) · Cigna Healthcare · GEHA · TRICARE · UMR · VA Community Care

Reprieve Recovery Center LLC – Trenton

20 Scotch Road, Trenton, NJ, 8628

4.9★★★★★66

Joint Commission

DetoxPHPIOP+3

Accepts InsuranceAccepts TRICARESelf-Pay

Co-occurring DisordersMATTrauma-informed+8

Reprieve Recovery Center LLC occupies 20 Scotch Road in Trenton, New Jersey. On record, this provider offers partial hospitalization, intensive outpatient and outpatient care. Substance use and mental health conditions are both treated here. This is outpatient provision, so daily life continues around the appointments. Federal registration is held through SAMHSA, and licensing sits with the New Jersey Division of Mental Health and Addiction Services.

0.5 miJohn S Watson Park1.1 miTrenton Mercer AirportServes43 towns

Substances treated

Levels of care

Therapies

Mental health

Groups served

Active Duty Military Dual Diagnosis Rehab · Active Duty Military Outpatient Rehab · Active Duty Military Rehab · Active Duty Military Telehealth · Active Duty Military Trauma Rehab · Active Duty Military TRICARE Rehab · Adult Rehab · Couples Rehab · Court Ordered Dual Diagnosis Rehab · Court Ordered MAT · +45 more

Support services

Insurance accepted

Aetna · Cigna Healthcare · Harvard Pilgrim Health Care · Health Net (Centene) · TRICARE · Tufts Health Plan · UMR · Unicare

More Addiction Rehabs Offering Lofexidine 13–80 of 1,327

Top of the World Ranch – 155th Avenue, Milan

3333 155th Avenue, Milan, Illinois, 61264

4.8★~~(174)~~

DetoxResidentialPHP+5Accepts InsuranceAccepts TRICARE+1

Live Again Detox – Nashville

1618 17th Avenue South, Nashville, Tennessee, 37212

4.8★~~(143)~~

DetoxResidentialPHP+3Accepts InsuranceAccepts TRICARE+1

FourPoints Health – Saint George

1449 North 1400 West, Saint George, Utah, 84770

4.9★~~(213)~~

DetoxIOPOutpatient+2Accepts InsuranceAccepts Medicaid+6

Serenity Ranch Recovery – Mammoth Cave

7415 Nolin Dam Road, Mammoth Cave, Kentucky, 42259

4.8★~~(124)~~

DetoxResidentialPHP+3Accepts InsuranceAccepts TRICARE+1

Victory Recovery Partners – Shirley

2 Coraci Boulevard, Shirley, NY, 11967

4.9★~~(212)~~

DetoxIOPOutpatient+2Accepts InsuranceAccepts Medicaid+5

Olympic Behavioral Health LLC – Lake Worth

3618 Lantana Road, Lake Worth, FL, 33462

4.8★~~(177)~~

DetoxPHPIOP+4Accepts InsuranceAccepts TRICARE+2

Reprieve LLC – West Palm Beach

4700 North Congress Avenue, West Palm Beach, FL, 33407

4.8★~~(144)~~

DetoxPHPIOP+3Accepts InsuranceAccepts TRICARE+1

East Coast Recovery – Cohasset

215 Chief Justice Cushing Highway, Cohasset, Massachusetts, 2025

4.8★~~(73)~~

DetoxPHPIOP+3Accepts InsuranceAccepts Medicaid+3

Top of the World Ranch – 36th Street, Milan

16016 36th Street, Milan, Illinois, 61264

4.8★~~(174)~~

DetoxResidentialTelehealth+2Accepts InsuranceAccepts TRICARE+1

Avenues Recovery Center at Norfolk – Norfolk

1516 Harmon Street, Norfolk, Virginia, 23518

4.7★~~(226)~~

DetoxResidentialPHP+4Accepts InsuranceAccepts Medicaid+3

Boca Recovery Center – Absecon

30 West Jimmie Leeds Road, Absecon, NJ, 8205

4.9★~~(518)~~

DetoxResidentialAftercareAccepts InsuranceAccepts Medicaid+3

Spinal Interventions – Provo

280 West River Park Drive, Provo, Utah, 84604

4.8★~~(1,292)~~

DetoxOutpatientTelehealth+1Accepts InsuranceAccepts Medicare+2

Evolutions Treatment Center – Fort Lauderdale

2901 West Cypress Creek Road, Fort Lauderdale, FL, 33309

4.7★~~(922)~~

DetoxPHPIOP+2Accepts InsuranceAccepts Medicaid+5

Asana Recovery – Fountain Valley

18101 Magnolia Street, Fountain Valley, California, 92708

4.8★~~(38)~~

DetoxPHPIOP+3Accepts InsuranceAccepts TRICARE+2

Eagle Healthworks – Thornville

14882 State Route 13, Thornville, OH, 43076

4.9★~~(59)~~

DetoxOutpatientTelehealth+1Accepts InsuranceAccepts Medicaid+3

Compassionate Recovery Care – Hermitage

4777 Andrew Jackson Parkway, Hermitage, Tennessee, 37076

4.9★~~(57)~~

DetoxOutpatientTelehealth+1Accepts InsuranceAccepts Medicaid+3

Milton Palm Beach Recovery – North Palm Beach

521 Northlake Blvd, North Palm Beach, FL, 33408

4.7★~~(86)~~

DetoxPHPIOP+4Accepts InsuranceAccepts Medicaid+3

Victory Recovery Partners – Farmingville

100 Granny Road, Farmingville, NY, 11738

4.7★~~(367)~~

DetoxIOPOutpatient+2Accepts InsuranceAccepts Medicaid+5

MCAT LLC – Cohasset

1 Chief Justice Cushing Highway, Cohasset, Massachusetts, 2025

4.8★~~(73)~~

DetoxResidentialTelehealth+1Accepts InsuranceAccepts Medicaid+3

Alchemy Addiction Recovery – Slidell

115 Christian Lane, Slidell, Louisiana, 70458

5.0★~~(20)~~

DetoxIOPOutpatient+2Accepts InsuranceAccepts Medicaid+2

Allure Detox – West Palm Beach

900 54th Street, West Palm Beach, FL, 33407

4.8★~~(236)~~

DetoxResidentialAftercareAccepts InsuranceAccepts TRICARE+1

RCC Community Services Inc – Pikesville

3 Greenwood Place, Pikesville, MD, 21208

4.9★~~(35)~~

DetoxOutpatientTelehealth+1Accepts MedicaidAccepts Medicare+1

Behavioral Health and – Chicago

2701 West 68th Street, Chicago, Illinois, 60629

4.6★~~(131)~~

DetoxHospital detoxInpatient+5Accepts InsuranceAccepts Medicaid+3

Hotel California by the Sea – Newport Beach

4504 Seashore Drive, Newport Beach, California, 92663

4.7★~~(211)~~

DetoxResidentialTelehealth+1Accepts InsuranceAccepts TRICARE+1

WhiteSands Alcohol and Drug Rehab – Tampa

215 West Verne Street, Tampa, FL, 33606

4.6★~~(213)~~

DetoxPHPIOP+3Accepts InsuranceAccepts TRICARE+3

I Am Recovery LLC – Pleasant Grove

3784 West Valley View Drive, Pleasant Grove, Utah, 84062

4.6★~~(110)~~

DetoxResidentialPHP+5Accepts InsuranceAccepts Medicaid+3

Asana Recovery | Outpatient Drug Rehab

1730 Pomona Ave, Costa Mesa, CA 92627, United States

4.6★~~(105)~~

DetoxHospital detoxInpatient+5Accepts InsuranceAccepts TRICARE+3

Guardian Recovery – Towaco

53 Indian Lane East, Towaco, NJ, 7082

4.8★~~(87)~~

DetoxResidentialAftercareAccepts InsuranceSelf-Pay

Kodiak Community Health Center – Kodiak

1911 Rezanof Drive, Kodiak, AK 99615

4.8★~~(52)~~

DetoxOutpatientTelehealth+1Accepts InsuranceAccepts Medicaid+7

Guardian Recovery – Portland

17 Bishop Street, Portland, ME 04103

4.6★~~(331)~~

DetoxResidentialIOP+2Accepts InsuranceAccepts Medicaid+1

WisHope Recovery Center – Waukesha

223 Wisconsin Avenue, Waukesha, Wisconsin, 53186

4.6★~~(103)~~

DetoxPHPIOP+4Accepts InsuranceAccepts Medicaid+5

Kaiser Permanente – Hillsboro

10315 NE Tanasbourne Drive, Hillsboro, Oregon, 97124

4.6★~~(768)~~

DetoxIOPOutpatient+2Accepts InsuranceAccepts Medicare

Mathers Recovery LLC – Fox Lake

101 Towne Center Lane, Fox Lake, Illinois, 60020

4.7★~~(150)~~

DetoxOutpatientTelehealth+1Accepts InsuranceAccepts Medicaid+4

Foundations Inpatient LLC – Windsor Mill

7131 Rutherford Road, Windsor Mill, MD, 21244

4.7★~~(91)~~

DetoxResidentialTelehealth+1Accepts InsuranceAccepts Medicaid+3

SolutionsRetreat Inc – Nashville

5405 Forest Acres Drive, Nashville, Tennessee, 37220

4.8★~~(63)~~

DetoxResidentialAftercareAccepts InsuranceAccepts TRICARE+3

Mountainside Chelsea, New York

243 West 18th Street, New York, NY, 10011

4.7★~~(73)~~

PHPIOPOutpatient+2Accepts InsuranceAccepts TRICARE+2

Hotel California by the Sea – Huntington Beach (18801 Flagstaff Lane)

18801 Flagstaff Lane, Huntington Beach, California, 92646

5.0★~~(17)~~

DetoxResidentialTelehealth+1Accepts InsuranceAccepts TRICARE+1

Hotel California by the Sea – Huntington Beach (19371 Worchester Lane)

19371 Worchester Lane, Huntington Beach, California, 92646

5.0★~~(17)~~

DetoxResidentialTelehealth+1Accepts InsuranceAccepts TRICARE+1

Hotel California by the Sea – Huntington Beach (19671 Ditmar Lane)

19671 Ditmar Lane, Huntington Beach, California, 92646

5.0★~~(17)~~

DetoxResidentialTelehealth+1Accepts InsuranceAccepts TRICARE+1

URP Lake Worth LLC – Lake Worth

Lake Worth, FL, 33461

4.7★~~(276)~~

DetoxResidentialAftercareAccepts InsuranceSelf-Pay

Evolutions Treatment Center – Miami

16565 NE 4th Avenue, Miami, FL, 33162

4.6★~~(500)~~

DetoxResidentialOutpatient+1Accepts InsuranceAccepts Medicaid+5

Brightview Health – Portsmouth

1405 11th Street, Portsmouth, OH, 45662

4.7★~~(65)~~

DetoxOutpatientTelehealth+1Accepts InsuranceAccepts Medicaid+4

Addictions Behavioral Health Center – Fort Lauderdale

1730 East Commercial Boulevard, Fort Lauderdale, FL, 33334

4.6★~~(51)~~

DetoxPHPIOP+3Accepts InsuranceSelf-Pay

Florida Addiction and Recovery Ctr – Fort Lauderdale

3601 West Commercial Boulevard, Fort Lauderdale, FL, 33309

4.6★~~(51)~~

DetoxPHPIOP+4Accepts InsuranceAccepts TRICARE+3

Farley Center – Williamsburg

5477 Mooretown Road, Williamsburg, Virginia, 23188

4.5★~~(329)~~

DetoxResidentialPHP+4Accepts InsuranceAccepts TRICARE+1

Palm Beach Recovery Centers – West Palm Beach

2700 Broadway Avenue, West Palm Beach, FL, 33407

4.6★~~(185)~~

DetoxHospital detoxInpatient+2Accepts InsuranceAccepts TRICARE+2

AMOS House – Providence

460 Pine Street, Providence, RI 02907

4.5★~~(377)~~

DetoxIOPOutpatient+3Accepts InsuranceAccepts Medicaid+2

Iris Health Clinic – Waukesha

255 West Broadway, Waukesha, Wisconsin, 53186

5.0★~~(9)~~

DetoxResidentialPHP+5Accepts InsuranceAccepts Medicaid+5

West Grove Clinic – Oak Creek

6416 South Howell Avenue, Oak Creek, Wisconsin, 53154

4.6★~~(69)~~

DetoxIOPOutpatient+2Accepts InsuranceAccepts Medicaid+4

Harbor Care – Nashua (45 High Street)

45 High Street, Nashua, NH 03060

4.5★~~(211)~~

DetoxPHPIOP+3Accepts InsuranceAccepts Medicaid+7

Elev8 Center New York LLC – New York

151 West 136th Street, New York, NY, 10030

4.6★~~(109)~~

DetoxResidentialTelehealth+2Accepts InsuranceAccepts Medicaid+4

Iris Healing Center – Woodland Hills

20300 Ventura Boulevard, Woodland Hills, California, 91364

4.8★~~(15)~~

DetoxPHPIOP+3Accepts InsuranceAccepts TRICARE+4

American Behavioral Clinics – Mequon

1240 West Ranchito Lane, Mequon, Wisconsin, 53092

4.6★~~(131)~~

DetoxOutpatientTelehealth+1Accepts InsuranceAccepts Medicaid+4

BrightView Health – Marietta

324 Pike Street, Marietta, OH, 45750

4.7★~~(37)~~

DetoxIOPOutpatient+1Accepts InsuranceAccepts Medicaid+5

BrightView Health – Springfield

201 North Yellow Springs Street, Springfield, OH, 45504

4.6★~~(49)~~

DetoxIOPOutpatient+2Accepts InsuranceAccepts Medicaid+5

Infinity Recovery – San Diego

9486 Owl Court, San Diego, California, 92129

4.7★~~(31)~~

DetoxResidentialTelehealth+1Accepts InsuranceAccepts TRICARE+2

BrightView Health – Chillicothe

126 East 2nd Street, Chillicothe, OH, 45601

4.6★~~(97)~~

DetoxOutpatientTelehealth+1Accepts InsuranceAccepts Medicaid+4

Complete Healthcare – Columbus (1539 West Broad Street)

1539 West Broad Street, Columbus, OH, 43222

4.6★~~(32)~~

DetoxPHPIOP+4Accepts InsuranceAccepts Medicaid+5

7 Summit Pathways – Tampa

1910 Orient Road, Tampa, FL, 33619

4.5★~~(60)~~

DetoxResidentialPHP+5Accepts InsuranceAccepts TRICARE+2

Harmony Place – Woodland Hills

23041 Hatteras Street, Woodland Hills, California, 91367

4.6★~~(109)~~

DetoxResidentialAftercareAccepts InsuranceAccepts Medicaid+4

Comunidades Latinas Unidas en Servicio – Saint Paul

797 East 7th Street, Saint Paul, Minnesota, 55106

4.5★~~(131)~~

DetoxIOPOutpatient+2Accepts InsuranceAccepts Medicaid+5

Kaiser Permanente Longview – Longview

1230 7th Avenue, Longview, WA, 98632

4.5★~~(1,235)~~

DetoxOutpatientTelehealth+1Accepts InsuranceAccepts Medicare+1

Kaiser Permanente/Mt Scott – Clackamas

9800 SE Sunnyside Road, Clackamas, Oregon, 97015

4.5★~~(1,034)~~

DetoxOutpatientTelehealth+1Accepts InsuranceAccepts Medicare

Kaiser Permanente – Tualatin

19185 SW 90th Avenue, Tualatin, Oregon, 97062

4.5★~~(546)~~

DetoxOutpatientTelehealth+1Accepts InsuranceAccepts Medicare

Restart Recovery – Calabasas

22405 Calipatria Drive, Calabasas, California, 91302

5.0★~~(9)~~

DetoxResidentialTelehealth+1Accepts InsuranceAccepts Medicaid+2

A Safe Place Empowerment Network Inc – Gastonia

260 West Main Avenue, Gastonia, North Carolina, 28052

5.0★~~(8)~~

DetoxIOPOutpatient+2Accepts InsuranceAccepts Medicaid+7

Hands on Health Associates LLC – Brooklyn

249 Pennsylvania Avenue, Brooklyn, NY, 11207

4.5★~~(58)~~

DetoxIOPOutpatient+2Accepts InsuranceAccepts Medicaid+4

VK New England Management LLC – Lawrence

320 Essex Street, Lawrence, Massachusetts, 1840

4.5★~~(133)~~

DetoxOutpatientTelehealth+1Accepts InsuranceAccepts Medicaid+4

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Common questions

Answered from what is listed here.

What is Lucemyra?

Lucemyra is the brand name for lofexidine, a non-opioid film-coated 0.18 mg tablet approved to ease the symptoms of opioid withdrawal in adults who stop opioids abruptly. It is an alpha-2 agonist, not a pain medicine, and is taken for a short course rather than long term.

Lofexidine had been marketed outside the United States since 1992 before the US approval, and DailyMed lists it under NDA 209229.

Medication Assisted Treatment (MAT)https://rehabseekers.com/medications/mat/

Is Lucemyra FDA approved?

Yes. The FDA approved Lucemyra on May 16, 2018 as the first non-opioid medicine for mitigation of withdrawal symptoms associated with abrupt discontinuation of opioids in adults. An advisory committee reviewed the application from US WorldMeds in March 2017 before that decision.

Development involved a grant from and collaboration with the National Institute on Drug Abuse.

Opioid Detox Programhttps://rehabseekers.com/programs/detox-centers/detox-by-substance/opioid-detox/

Is Lucemyra a treatment for opioid use disorder?

No. Lucemyra eases withdrawal symptoms but is not a treatment for opioid use disorder, and the manufacturer states that withdrawal management alone, with or without Lucemyra, is not recommended for someone with opioid use disorder. It is labeled for use inside a comprehensive management program.

A 2020 review describes it as a way to manage acute withdrawal before starting methadone or buprenorphine maintenance.

Suboxone and Buprenorphinehttps://rehabseekers.com/medications/mat/buprenorphine/

Is Lucemyra an opioid?

No. The manufacturer's patient information states that Lucemyra is not an opioid and will not produce the effects seen when taking opioids. It works on alpha-2 receptors to blunt the physical symptoms that follow abrupt opioid discontinuation, such as sweating, chills, cramps and restlessness.

The FDA's own review found lofexidine does not bind receptors linked to misuse potential.

Opioid Detoxhttps://rehabseekers.com/addictions/opioid/opioid-detox/

Is Lucemyra a controlled substance?

No. The DailyMed label lists DEA Schedule as None, and the FDA's Controlled Substance Staff agreed in 2018 that lofexidine does not warrant placement in any schedule of the Controlled Substances Act. It is still a prescription medicine and must be prescribed by a clinician.

That review cited several years of use in the United Kingdom without signals of misuse.

Prescriber Accesshttps://rehabseekers.com/medications/prescriber-access/

Will Lucemyra stop opioid cravings?

No. The manufacturer's safety information says Lucemyra will not stop cravings for opioids, and that it may lessen the severity of withdrawal symptoms without completely preventing them. It addresses the physical discomfort of withdrawal, not the drive to use.

Medications such as buprenorphine, methadone or naltrexone are the ones used to address ongoing opioid use disorder.

Naltrexone Treatmenthttps://rehabseekers.com/medications/mat/naltrexone/

How many Lucemyra tablets do you take a day?

The usual starting dose is three 0.18 mg tablets taken by mouth four times daily, 5 to 6 hours apart, which is 12 tablets or 2.16 mg a day, during peak withdrawal in the first 5 to 7 days after the last opioid dose. The label caps use at 16 tablets, or 2.88 mg, daily.

No single dose should exceed four tablets, and dosing is adjusted to symptoms.

Medical Detoxhttps://rehabseekers.com/programs/detox-centers/medical-detox/

How long can you take Lucemyra?

Up to 14 days. The label allows treatment for as long as two weeks with dosing guided by symptoms, and some payer criteria note that 3 to 7 days is often enough. The medicine is then stopped with a gradual reduction over 2 to 4 days rather than all at once.

A typical taper drops one tablet per dose every one to two days.

Detox Centershttps://rehabseekers.com/programs/detox-centers/

How do you stop taking Lucemyra?

Gradually. The label directs a dose reduction over 2 to 4 days, for example one fewer tablet per dose every one to two days, rather than stopping abruptly, because a sudden stop can raise blood pressure. The prescriber sets the taper schedule based on symptoms.

Ask the program what ongoing treatment is planned for once the course ends.

Discharge Planninghttps://rehabseekers.com/programs/aftercare-and-continuing/discharge-planning/

Does Lucemyra lower blood pressure?

Yes. The label warns that Lucemyra can lower blood pressure and pulse and cause fainting, and directs that the next dose be reduced, delayed or skipped if low blood pressure or a slow pulse becomes significant or causes symptoms. Standing up from lying down raises the risk.

Patients are taught to sit or lie down and rise carefully while taking it.

Clonidine and Lofexidine Detoxhttps://rehabseekers.com/programs/detox-centers/detox-by-substance/non-opioid-detox-medication/

What are the side effects of Lucemyra?

The common effects are low blood pressure or lightheadedness, a slow heart rate, dizziness, sleepiness and dry mouth. Lucemyra also prolongs the QT interval: a Phase 3 study showed a maximum mean QTcF increase of 7.3 ms at 2.16 mg a day and 9.3 ms at 2.88 mg a day.

Side effects can be reported to BioCorRx at 1-833-LUCEMYRA or to FDA MedWatch at 1-800-FDA-1088.

Hospital Detoxhttps://rehabseekers.com/programs/detox-centers/hospital-detox/

Can you take Lucemyra with Suboxone or methadone?

Sometimes, but only under a prescriber's direction. The label found no interaction with buprenorphine and no change in methadone levels, yet QT prolongation was greater in combination: 15 ms added over buprenorphine alone and 9.1 ms over methadone alone at the 2.88 mg daily dose.

If you take methadone or other QT-prolonging medicines, ask whether an ECG is done before starting.

Methadone Maintenancehttps://rehabseekers.com/medications/mat/methadone/methadone-maintenance/

Can you drink alcohol or take benzodiazepines with Lucemyra?

No, not without medical advice. The manufacturer's patient information says alcohol, barbiturates and benzodiazepines should be used with caution alongside Lucemyra because serious side effects may occur, including deeper sedation and greater drops in blood pressure.

Tell the prescriber about every medicine being taken, including anything used during opioid discontinuation.

Benzodiazepine Rehabhttps://rehabseekers.com/addictions/benzodiazepine/

Can I take Lucemyra at home?

Yes, the label allows outpatient use, but it depends on being able to self-monitor. Anyone taking it outside a facility must watch for signs of low blood pressure and a slow pulse, hold a dose when symptoms appear and call the prescriber. Vital signs are checked at visits.

Clinical trials supporting the medicine monitored patients before each dose in an inpatient setting.

Outpatient Detoxhttps://rehabseekers.com/programs/detox-centers/outpatient-detox/

Is there a generic for Lucemyra?

Yes. Indoco Remedies announced final FDA approval of a generic lofexidine 0.18 mg tablet in August 2024, reported as the first generic of Lucemyra and carrying a Competitive Generic Therapy designation with 180 days of exclusivity. An authorized generic is also sold in 36-count and 96-count bottles.

BioCorRx acquired Lucemyra from USWM, LLC under an agreement announced in March 2025.

Self Pay Rehabhttps://rehabseekers.com/payment/self-pay/

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Lofexidine, sold as Lucemyra, is a non-opioid tablet taken for up to 14 days to ease the symptoms that come when an adult stops opioids abruptly. It is not an opioid, and it is not a treatment for opioid use disorder on its own.

That distinction shapes everything else. Lofexidine makes the days of acute withdrawal easier to sit through; what happens after those days is a separate decision about buprenorphine, methadone, naltrexone or counseling. The manufacturer’s own patient information says the medication will not stop cravings for opioids and may lessen withdrawal symptoms without preventing them.

This page covers what lofexidine is approved for, how it is dosed and stopped, the blood pressure and heart rhythm cautions that drive monitoring, who prescribes and dispenses it, what a course costs, how plans handle prior authorization, and how to find a program that uses it.

What Is Lofexidine (Lucemyra)?

Lofexidine hydrochloride is a film-coated 0.18 mg oral tablet, sold under the brand name Lucemyra. The FDA approved it on May 16, 2018 as the first non-opioid treatment for mitigation of withdrawal symptoms associated with abrupt discontinuation of opioids in adults. DailyMed lists its DEA schedule as None.

The label indication is narrow: easing withdrawal symptoms to make abrupt opioid discontinuation workable. The 2018 launch material states plainly that Lucemyra is not an opioid, is not a treatment for opioid use disorder, and that withdrawal management alone, with or without the medication, is not recommended for someone with opioid use disorder. It is labeled for use inside a comprehensive management program.

Lofexidine had been marketed outside the United States since 1992, and its US development involved a grant from and collaboration with the National Institute on Drug Abuse. FDA’s Controlled Substance Staff agreed in 2018 that it does not warrant scheduling, noting it does not bind receptors linked to misuse potential and had years of United Kingdom use without misuse signals.

A bridge, not a destination. A 2020 review describes lofexidine as a way to manage acute withdrawal before starting maintenance treatment with methadone or buprenorphine. In the directory, detox is recorded at virtually every program that stocks it, and transfer arrangements between programs are over-represented, which matches that place in the sequence.

How Is Lofexidine Taken and for How Long?

The usual starting dose is three 0.18 mg tablets by mouth four times daily, 5 to 6 hours apart, during peak withdrawal, generally the first 5 to 7 days after the last opioid dose. That is 12 tablets, or 2.16 mg, a day. The label caps dosing at 16 tablets (2.88 mg) a day and 4 tablets in any single dose.

Treatment may continue for up to 14 days, with dosing guided by symptoms, and is then stopped with a gradual reduction over 2 to 4 days, for example one fewer tablet per dose every 1 to 2 days. Stopping abruptly can raise blood pressure, which is why the taper is written into the label rather than left to judgment.

Safety was supported by three randomized placebo-controlled trials enrolling 935 adults dependent on short-acting opioids, with participants monitored before each dose in an inpatient setting. Study 1 measured symptoms using the Short Opiate Withdrawal Scale of Gossop, scored 0 to 30, once daily on Days 1 to 7.

What Monitoring Does Lofexidine Need?

Blood pressure and pulse. The label warns that lofexidine can lower both and cause fainting, and directs that the next dose be reduced, delayed or skipped if low blood pressure or slow pulse becomes clinically significant or causes symptoms. Prescribers are told to teach patients that standing up from lying down raises the risk, and to rise carefully.

Heart Rhythm and Other Medications

Lofexidine prolongs the QT interval. In a Phase 3 dose-response study the maximum mean QTcF prolongation was 7.3 ms at 2.16 mg a day and 9.3 ms at 2.88 mg a day. Added to methadone at 80 to 120 mg a day it raised maximum mean QTcF by 9.1 ms, and added to buprenorphine at 16 to 24 mg a day by 15 ms. No pharmacokinetic interaction was found with either. QTc prolongation was more pronounced with severe hepatic or severe renal impairment.

Who Needs Closer Watching

Individuals lacking the CYP2D6 enzyme, roughly 8% of Caucasians and 3 to 8% of Black or African American individuals, are likely to have about 28% higher exposure, so blood pressure and pulse are watched. At 2.88 mg a day the label reports serious cardiovascular adverse events in 4 of 101 women (4%) against 3 of 289 men (1%). Alcohol, barbiturates and benzodiazepines are to be used with caution alongside it. Safety in pregnancy has not been established; animal studies showed increased stillbirths and litter loss.

Who Prescribes Lofexidine and Where Is It Dispensed?

Lofexidine is an ordinary retail prescription, filled at a pharmacy counter rather than dispensed through an opioid treatment program. At launch, promotion went to primary care physicians, pain management specialists, psychiatrists working in addiction medicine and other addiction medicine specialists. BioCorRx describes supply through national wholesalers, specialized distributors, retail pharmacies and institutional pharmacies.

Some plans narrow who may write it. Kaiser Permanente Northwest covers Lucemyra when it is prescribed by or in consultation with a pain management or addiction medicine specialist. Oklahoma Medicaid requires the prescriber to verify screening for liver and kidney impairment, that vital signs were monitored, and that the member was taught to self-monitor for low blood pressure and slow pulse.

BioCorRx Pharmaceuticals announced an agreement to acquire Lucemyra from USWM, LLC on March 10, 2025, and in August 2026 published new package codes under labeler code 85789 for both the brand and an authorized generic, with the earlier codes continuing to supply the market during the change. Indoco Remedies announced FDA approval of the first generic lofexidine 0.18 mg tablet in August 2024, carrying Competitive Generic Therapy designation and 180 days of exclusivity.

How Much Does Lofexidine Cost?

A full 14-day course at the 16-tablet daily maximum is 224 tablets. At the average pharmacy acquisition cost of $9.23846 per tablet listed for July 22, 2026, that comes to about $2,069 before any pharmacy markup. A 2020 pharmacy review said a 14-day supply in the United States can cost up to $3,000 and called price a barrier to use.

Discount-card prices vary sharply by counter. On October 24, 2026, SingleCare listed 36 Lucemyra tablets at $143.75 at CVS, $299.16 at Walgreens, $320.38 at Publix, $504.45 at Food Lion, $631.37 at Costco, $749.47 at Kroger and $802.47 at Walmart near one Virginia ZIP code. The 2018 launch copay program offered eligible patients the medication for as little as $25 but excluded prescriptions paid in whole or part by Medicare, Medicaid or similar programs; whether that program still runs under the current owner is worth asking the pharmacy.

The medication sits inside a detox episode, so the surrounding care carries its own price. Medical detox commonly runs $1,540 to $5,600 a week, or $220 to $800 a day, before any coverage is applied.

Typical US market rates before insurance
Level of care	Monthly	Daily
Medical detox (7–14 days)	$1,500 – $5,200 per week	$215 – $745
Residential inpatient	$6,200 – $26,000	$205 – $865
PHP	$7,200 – $14,000	$240 – $465
IOP	$2,700 – $9,200	$90 – $305
Outpatient	$1,300 – $5,200	$45 – $175

Does Insurance Cover Lofexidine?

Often, with prior authorization and a quantity limit. Wellmark sets an initial limit of 224 tablets per 90 days, one full 14-day course, and allows a second course (448 tablets per 90 days) with authorization where there have been multiple attempts to stop opioids within three months. Kaiser Permanente Northwest requires regular opioid use for at least two weeks plus documented withdrawal symptoms or a planned dose reduction expected to cause them.

A clonidine step is the common gate. Kaiser Permanente Northwest requires a failed trial of, or contraindication or intolerance to, clonidine, and caps treatment at 14 days while noting 3 to 7 days is often sufficient. Ohio Medicaid’s Unified Preferred Drug List effective July 1, 2026 lists Lucemyra as non-preferred with prior authorization limited to 14 days, asking for justification why a buprenorphine or methadone taper cannot be used and an inadequate response or contraindication to clonidine, with an exemption where the drug was started inpatient.

Other states set their own terms. Oklahoma Medicaid approves a maximum of 14 days at 12 tablets daily and asks for the date of opioid discontinuation. Delaware’s 2026 preferred drug list places it among non-preferred opioid treatment agents, requiring two preferred products first. Louisiana Medicaid requires diagnosis code F11.13, F11.23 or F11.93, denies claims for beneficiaries 17 or younger, and caps a fill at 224 tablets. The VA Formulary Advisor lists lofexidine as non-formulary at copay tier 2, so a non-formulary request and prior approval are needed. Medicare Part D and TRICARE rules were not available for this page, so Medicare and TRICARE members should ask the plan directly about tier, authorization and quantity limit.

Ask the program before the last opioid dose

Will clonidine or a buprenorphine or methadone taper be tried first?

Would the first doses be given in a monitored inpatient or emergency setting?

How are blood pressure and pulse checked, and whom do I call when a dose should be held?

Is an ECG done first if I am on methadone or another QT-prolonging medicine?

Are the prior authorization and first fill arranged before I stop opioids, and what treatment continues after day 14?

How Do I Find a Program That Uses Lofexidine Near Me?

Start with a withdrawal management or addiction medicine clinician: a primary care physician, a county access line, or a detox program’s admissions team can say whether lofexidine is on hand. Your plan’s drug list and pharmacy search will show tier, authorization and quantity limit. The Lucemyra website also runs a Find a Provider tool, with a Spanish-language patient brochure and a caregiver guide.

Programs offering lofexidine are gathered on this page alongside the wider medication assisted treatment listings, with pages for medical detox, outpatient detox and opioid detox. Each listing shows levels of care, accepted payments, licensing and accreditation, and distance to the nearest airport. Stocking is recorded most heavily in New York, with California close behind, then Ohio, Arizona and Kentucky, which follows federal reporting rather than any ranking of provision.

What Is the Difference Between Lofexidine and Clonidine?

Both are alpha-2 agonists used to blunt opioid withdrawal, but only lofexidine carries an FDA approval for that use; clonidine is a low-cost generic used off label. That cost gap is why Kaiser Permanente Northwest, Oklahoma Medicaid and Ohio Medicaid all ask for a clonidine trial, contraindication or intolerance before paying for lofexidine. Neither medication treats opioid use disorder, and neither stops cravings.

In March 2026 the FDA sent BioCorRx an untitled letter calling a website claim that Lucemyra is the only FDA-approved non-opioid medicine for opioid withdrawal symptoms misleading, since other approved lofexidine products exist, and saying benefit claims were presented more prominently than risk information. Side effects can be reported to the manufacturer at 1-833-LUCEMYRA or to FDA MedWatch at 1-800-FDA-1088.

References and Citations

US Food and Drug Administration — Lucemyra (lofexidine) prescribing information, Controlled Substance Staff review, approval timeline and March 2026 untitled letter.
DailyMed — Lucemyra 0.18 mg tablet label record, NDA 209229, package listings and DEA schedule.
US WorldMeds, Salix Pharmaceuticals and BioCorRx Pharmaceuticals — launch, acquisition and NDC transition announcements, and patient safety information.
Ohio Department of Medicaid, Oklahoma Health Care Authority, Delaware Medicaid, Louisiana Medicaid, Kaiser Permanente Northwest, Wellmark and VA Formulary Advisor — coverage criteria and quantity limits.
RehabSeekers directory listings and market rate research, United States, 2026. Ranges are indicative and vary by facility, length of stay and coverage.